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The image shows mitotic metaphase (upper) and anaphase (lower) in Drosophila tissue culture cells immunostained for the microtubule severing protein katanin (green), microtubules (red) and kinetochores/chromosomes (blue). Katanin targets to chromosomes during both metaphase and anaphase and is responsible for inducing the depolymerization of attached microtubule plus-ends.